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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GYS1 All Species: 18.18
Human Site: T392 Identified Species: 28.57
UniProt: P13807 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13807 NP_002094.2 737 83786 T392 V R K Q L W D T A N T V K E K
Chimpanzee Pan troglodytes XP_520790 703 80912 M368 T V V V F F I M P A K T N N F
Rhesus Macaque Macaca mulatta Q8MJ26 737 83768 T392 V R K Q L W D T A N T V K E K
Dog Lupus familis XP_534869 703 80957 M368 T V V V F F I M P A K T N N F
Cat Felis silvestris
Mouse Mus musculus Q9Z1E4 738 83908 T392 V R K Q L W D T A N T V K E K
Rat Rattus norvegicus A2RRU1 738 84053 T392 V R K Q L W D T A N T V K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505471 733 83148 T392 V R K Q L W D T A N T V K E K
Chicken Gallus gallus XP_416432 704 81032 F367 D V T V V V F F I M P A K T N
Frog Xenopus laevis NP_001084863 702 80811 F367 D V T V V V F F I M P T K T N
Zebra Danio Brachydanio rerio NP_957474 700 80455 F366 E V T V I A F F I M P A R T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VFC8 709 81735 N367 A G R Y E F G N K G A D I F I
Honey Bee Apis mellifera XP_624707 692 79590 A357 G A D I F I E A L A R L N H Y
Nematode Worm Caenorhab. elegans Q9U2D9 672 76441 D339 G H L D F D L D K T L Y F F T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23337 708 80492 V375 A L K S Q A I V K S L E N T V
Red Bread Mold Neurospora crassa O93869 706 80888 K373 L K G Q A V I K S L R D T V D
Conservation
Percent
Protein Identity: 100 68.6 99 69.3 N.A. 96.6 96.6 N.A. 90 71 69.3 78.1 N.A. 55 56.4 49.6 N.A.
Protein Similarity: 100 81.8 99.5 82.5 N.A. 98.5 98.5 N.A. 95.2 84.1 82.5 86.5 N.A. 71 70.1 65.8 N.A.
P-Site Identity: 100 0 100 0 N.A. 100 100 N.A. 100 6.6 6.6 0 N.A. 0 0 0 N.A.
P-Site Similarity: 100 6.6 100 6.6 N.A. 100 100 N.A. 100 13.3 13.3 13.3 N.A. 13.3 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50 51.1
Protein Similarity: N.A. N.A. N.A. N.A. 67.1 67
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 0 7 14 0 7 34 20 7 14 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 7 7 0 7 34 7 0 0 0 14 0 0 7 % D
% Glu: 7 0 0 0 7 0 7 0 0 0 0 7 0 34 0 % E
% Phe: 0 0 0 0 27 20 20 20 0 0 0 0 7 14 14 % F
% Gly: 14 7 7 0 0 0 7 0 0 7 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 7 7 7 27 0 20 0 0 0 7 0 7 % I
% Lys: 0 7 40 0 0 0 0 7 20 0 14 0 47 0 34 % K
% Leu: 7 7 7 0 34 0 7 0 7 7 14 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 14 0 20 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 34 0 0 27 14 20 % N
% Pro: 0 0 0 0 0 0 0 0 14 0 20 0 0 0 0 % P
% Gln: 0 0 0 40 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 7 0 0 0 0 0 0 0 14 0 7 0 0 % R
% Ser: 0 0 0 7 0 0 0 0 7 7 0 0 0 0 0 % S
% Thr: 14 0 20 0 0 0 0 34 0 7 34 20 7 27 7 % T
% Val: 34 34 14 34 14 20 0 7 0 0 0 34 0 7 7 % V
% Trp: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _